Mineral Deficiency
People with uncontrolled hyperglycemia, especially those on chronic diuretic therapy, are prone to develop deficiencies in some minerals, notably potassium, magnesium, and zinc. Deficiencies of certain minerals such as potassium, magnesium, and possibly zinc and chromium may predispose one to carbohydrate intolerance.
The need for potassium or magnesium replacement is easily accepted because the effects of overt potassium or magnesium deficiency, especially on the cardiovascular system and skeletal muscles, are profound and readily detectable. The deficiency state of potassium and magnesium is relatively easy to detect based on low serum levels.
The consequences of zinc and chromium deficiency are slow to emerge, and the need for supplementation is more difficult to ascertain. Several small studies have found that chromium supplementation improves glucose intolerance, gestational diabetes, and corticosteroid-induced diabetes