Strategies to enhance the absorption of various nutrients in the body.
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Nutrients
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Role in Body
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Impaired Utilization or Absorption
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Strategies to Enhance Availability
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Protein
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Muscle and bone development,
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Insulin resistance.
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Increased aerobic exercise can have positive effect on protein anabolism and reduce insulin resistance by increasing microvascular supply of amino acid.
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Fracture reduction.
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Protein anabolic resistance.
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Iron
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Oxygen transport,
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Increased non-heme iron levels in body organs (brain, heart, liver, kidney)
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Iron chelation therapy in case of excess iron accumulation
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Hormone synthesis,
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Increased hepcidin levels
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Dietary intake of heme and non-heme sources of iron like meat and meat products, fish (tuna, sardine), egg, fortified breakfast cereals, dry fruits, dark green vegetables, soyabean, chickpea, tofu, kidney beans, lentil etc.
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Component of enzymes and cytochrome and plays role in electron transport,
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Regular usage of aspirin
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Thyroid metabolism.
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Calcium
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Osteoporotic fracture prevention,
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High sodium diet increases urinary calcium loss.
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Diet rich in calcium and supplementation of calcium and vitamin D3 in case of severe hypocalcemia.
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Maintenance of bone health,
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Oxalates in spinach, walnuts and sorrel, tannins in tea and phytate in bran, nuts, seeds and most cereals reduces intestinal calcium absorption.
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Regulation of neurotransmitters and nerve excitability.
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Inadequate Vitamin D3 levels.
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Zinc
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Normal functioning of immune system,
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Altered zinc transporter expression due to epigenetic dysregulation affects zinc homeostasis.
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Intake of zinc supplementation.
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Anti-inflammatory properties,
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Degenerative alterations in intestine with age.
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Prevention of apoptosis, Taste acuity, Cognitive functioning.
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Magnesium
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Neuromuscular excitability,
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Altered vitamin D3 metabolism decreases intestinal absorption.
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Adequate dietary intake of magnesium rich foods like whole grains, green leafy vegetables, beans, nuts and fruits.
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Co-factor for protein synthesis and nucleic acid synthesis.
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Use of excessive diuretics reduces Mg reabsorption.
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Vitamin D3
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Intestinal calcium absorption,
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Lower cutaneous Vitamin D3 synthesis.
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Supplementation of vitamin D3.
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Maintenance of muscular strength,
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Prevention of osteoporosis and osteomalacia.
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Vitamin B12
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Improve cognitive performance,
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Malabsorption due to gastrointestinal disorders.
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Consumption of B-complex or multivitamin supplements containing 1000 mcg cobalamin daily.
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Breakdown of homocysteine (risk factor for cardiovascular diseases).
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Excess use of drugs that interfere with B12 absorption.
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Food-cobalamin malabsorption syndrome
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Intestinal malabsorption.
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Vitamin B9
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Improve cognitive performance,
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Intestinal malabsorption due to atrophic gastritis.
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Vitamin B supplementation.
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Metabolism of homocysteine (risk factor for cardiovascular diseases),
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Long term intake of high doses of gastric acid secretion suppressor drugs.
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Formation of nerve tissues and blood cells,
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Synthesis of nucleic acid.
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Vitamin B6
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Improve cognitive performance,
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Altered protein metabolism and inflammation by chronic diseases.
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Vitamin B supplementation.
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Breakdown of homocysteine (risk factor for cardiovascular diseases),
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Co-factor for enzymes involved in synthesis, catabolism, decarboxylation, transformation of amino acid and metabolism of nucleic acid and lipids.
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